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Wang Chun

M.D., Ph.D.,Director of the department of Hematology, Chief Physician, Professor of Medicine, Doctoral Supervisor

Diagnosis and treatment of blood disease and bone marrow transplantation

Department of Hematology

Profile

Education and training
1988-1991 Doctor Degree
Department of Hematology, Tongji Medical University, Wuhan, Hubei, China
1983-1986 Master Degree
Department of Hematology, Shanxi Medical University, Taiyuan, Shanxi, China
1978-1983 Bachelor Degree

Wan’na Medical College, Wuhu,Anhui, China


Professional Membership:
Chairman, Shanghai Hematology Committee of Chinese Medical Association 2014-2016
Committee member, Leader of Anti-infection working group, Hematology Committee of Chinese Medical Association
Committee member, China anticancer association blood tumor Specialized Committee
Committee member, Hematology branch of Chinese medical doctor association


Work Experiences:
1998--present Director, Department of Hematology, Shanghai General Hospital, Shanghai  Jiao Tong University, Shanghai,
China
1996-1998 Postdoctoral fellow
Bone marrow transplantation center, Ontario Cancer Institute, Ontario
Canada
1986-1996 Vice Director
Department of Hematology
Shanxi Medical University Affiliated Second Hospital, Taiyuan, Shanxi, China


Recent publications:
(1)Wan Liping, Zhang Y, Lai Y, Jiang M, Song Y, Zhou J, Zhang Z, Duan X, Fu Y, Liao L, Wang C. Effect of Granulocyte-Macrophage Colony-Stimulating Factor on Prevention and Treatment of Invasive Fungal Disease in Recipients of Allogeneic Stem-Cell Transplantation: A Prospective Multicenter Randomized Phase IV Trial. Journal of Clinical Oncology. 2015; 33(34): 3999-4006.
(2)Yang Juan,Cai Y, Jiang JL, Wan LP, Yan SK, Wang Chun. Anti-thymocyte globulin could improve the outcome of allogeneic hematopoietic stem cell transplantation in patients with highly aggressive T-cell tumors. Blood Cancer Journal. 2015 Jul 31;5:e332. doi: 10.1038/bcj.2015.54.
(3)Zou J, Zhou Z, Wan L, Tong Y, Qin Y, Wang C, Zhou K. Targeting the Sonic Hedgehog-Gli1 Pathway as a Potential New Therapeutic Strategy for Myelodysplastic Syndromes. PLoS One. 2015; 28;10(8): e0136843.
(4)Jiang Y, Wan L, Qin Y, Wang X, Yan S, Xie K, Wang C.Donor Chimerism of B Cells and Nature Killer Cells Provides Useful Information to Predict Hematologic Relapse following Allogeneic Hematopoietic Stem Cell Transplantation. PLoS One. 2015 Jul 30;10(7):e0133671. doi: 10.1371
(5)Zou J, Hong Y, Tong Y, Wei J, Qin Y, Shao S, Wang C, Zhou K.Sonic hedgehog produced by bone marrow-derived mesenchymal stromal cells supports cell survival in myelodysplastic syndrome. Stem Cells Int. 2015; 957502.
(6)Zhou Z, Wan L, Wang C, Zhou K.Integration of Shh and Wnt Signaling Pathways Regulating Hematopoiesis. DNA Cell Biol. 2015 ;34(12):710-6.
(7)Wan L, Wang C, Liu L, Tang X, Wang J, Guan Y, Jiang M, Duan X, Ke X, Jing H, Hu J, Wang L, Li Y, Geng L. Efficacy and safety of micafungin as prophylaxis for invasive fungal disease in neutropenic patients with hematologic malignancies. International Journal of Pharmacology. 2014; 10 (4): 231-236.
(8)Yao Y, Wang C, Wei W, Shen C, Deng X, Chen L, Ma L, Hao S.Dendritic cells pulsed with leukemia cell-derived exosomes more efficiently induce antileukemic immunities. PLoS One. 2014,9(3): e91463.
(9)Zhou L, Bai H, Wang C, Wei D, Qin Y, Xu X. microRNA125b promotes leukemia cell resistance to daunorubicin by inhibiting apoptosis.Mol Med Rep. 2014, 9(5):1909-16.
(10)Shao S, Li S, Qin Y, Wang X, Yang Y, Bai H, Zhou L, Zhao C, Wang C.Spautin-1,a novel autophagy inhibitor,enhances imatinib induced apoptosis in chronic myeloid leukemia. Int J Oncol.  2014,44(5):1661-8.
(11)Jiang Y, Wan L, Qin Y, Wang X, Yan S, Xie K, Wang C. Chimerism status is correlated to acute graft-versus-host disease after allogeneic stem cell transplantation.Int J Hematol. 2014,99(3):323-8.
(12)Shao S, Huang X, Wang Y, He S, Xu X, Zhu X, Yang X, Ding Z, Yao L, Huang Y, Wang C.A role for activator of G-protein signaling 3 (AGS3) in multiple myeloma.Int J Hematol. 2014,99(1):57-68.
(13)Xu X, Li B, Huang P, Wan X, Qin Y, Zhou L, Liu H, Bai H, Gao Y, Wang C, Meng X. Citrate induces apoptosis of the acute monocytic leukemia U937 cell line through regulation of HIF-1a signaling. Mol Med Rep. 2013,8(5):1379-1386.
(14)Xu X, Wang C, Wang Y, Zhou L, Bai H. Rituximab and Fludarabine or Cyclophosphamide Combination Treatment for Older Waldenstrom Macroglobulinemia Patients. Turk J Hematol. 2013,30(4):336-337.
(15)Liu H, Qin Y, Wang X, Xie K, Yang Y, Zhu J, Zhao C, Wang C.  Polyclonal rabbit antithymocyte globulin induces apoptosis and has cytotoxic effects on human leukemic cells. Clin Lymphoma Myeloma Leuk. 2012,12(5),345-354.
(16)Wei J, Wang C, Qin YW, Zhu J, Gao YR, Cai Q, Yan SK.JAK2 V617F positive essential thrombocythemia developing in a patient with CD5⁻chronic lymphocytic leukemia. Chin Med J (Engl).2012,125(11), 2076-2079.
(17)Shen C, Hao SG, Zhao CX, Zhu J, Wang C. Antileukaemia immunity: effect of exosomes against NB4 acute promyelocytic leukaemia cells. J Int Med Res.2011,39(3), 740-747.
(18)Wang X,Wang C, Qin YW, Yan SK, Gao YR. The association of up-regulation of X-linked inhibitor of apoptosis protein with cell adhesion-mediated drug resistance in U937 cells. Hematol Oncol.2008, 26(1), 21-26。
(19)Wang X, Wang C, Qin YW, Yan SK, Gao YR. Simultaneous suppression of multidrug resistance and antiapoptotic cellular defense induces apoptosis in chemoresistant human acute myeloid leukemia cells. Leukemia Research. 2007;31(7):989-94.
(20)Wang Chun, Chun Wang on Oncology in China. Lancet Oncol. 2(7), 450-453, 2001.


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